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Natarajan Kannan

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Professor of Biochemistry & Molecular Biology
Professor of the Institute of Bioinformatics
Georgia Cancer Coalition Distinguished Scholar

Dr. Kannan's research is focused on the grand challenge of mapping genome-phenome relationships in biomedically important proteins using computational and experimental approaches. His laboratory has made impactful contributions in defining the unique modes of regulation in various protein families, including protein kinases, glycosyltransferases, and ion channels. Dr. Kannan has published nearly 100 peer-reviewed articles with over 6000 citations and an h-index 41. He has trained over 30 undergraduate, graduate, and post-graduate trainees, junior scientists, and young investigators and has received multiple state and national awards, including the Georgia Coalition Distinguished Scholar Award, National Science Foundation CAREER award, NIH Maximizing Research Investigator Award, and UGA Creative Research Award. See for more details.

  • Georgia Cancer Coalition Distinguished Cancer Scholar
  • Cold Spring Harbor Laboratory, New York, Postdoc
  • University of California, San Diego, Postdoc
  • Indian Institute of Science, Bangalore, Ph.D., 2001
Research Interests:

My lab is focused on pursuing rigorous and deep biological questions connecting protein sequence, structure, function, and regulation as an essential step toward inferring causal genome-phenome relationships. We focus on large gene families such as protein kinases, glycosyltransferases, and ion channels contributing to diverse cellular and disease phenotypes. Over the years, we have developed and deployed a powerful evolutionary systems approach to generate and test models of protein evolution and allosteric regulation. More recently, we have leveraged advances in artificial intelligence and large protein language models for protein design and classification. 

Other Website:
Articles Featuring Natarajan Kannan

Claire Bunn, an undergraduate researcher in Professor Kannan’s laboratory and a third-year Foundation Fellow and Stamps Scholar (majoring in genetics, minoring in statistics), is among 410…

Congratulations to Aarya Venkat (Kannan Lab) for winning the People’s Choice Award at the 3 MT Thesis competition! If you missed the competition, visit the Graduate School’s website (…

Natarajan Kannan, associate professor in the Department of Biochemistry and Molecular Biology and the Institute of Bioinformatics, employs a multi-disciplinary approach to understand fundamental functions of biomedically important protein…

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