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The Dalton laboratory is interested in how ‘molecular medicine’ can be used to understand human disease, for the purpose of developing new therapies and cures.

Pluripotent stem cells are being in the Dalton laboratory to decipher the molecular and cellular basis of human disease and to understand mechanisms of tissue regeneration. Important outcomes from these translational studies include the development of cell-based and small molecule-based therapeutics in a range of clinical areas for which there are no current therapies or treatments. Focus areas for the Dalton laboratory include building new blood vessels (vascular engineering) for use in areas such as peripheral artery disease, cardiovascular disease, traumatic injury and stroke. A second area of interest focuses on the development of new drugs that can be used to treat metabolic diseases such as type 2 diabetes. We are also developing transplantation approaches for diabetic patients using stem cell technology. Here, we collaborate with tissue engineers and transplant biologists in this multidisciplinary project aimed at curing human metabolic disease. See for more details. The Dalton laboratory is located in the new Center for Molecular Medicine (

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