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For any changes or ammendments to the information
below, please email puett@bmb.uga.edu or by phone at (706) 524-0004.
Faculty / Staff
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Susanne
Warrenfeltz — Assistant Research Scientist
Tel Office: (706) 542-1724
Tel Lab: (706) 542-3321
Molecular
Mechanisms of Ovarian Cancer Progression
Insulin-like growth factor (IGF) is a potent mitogenic and survival
factor implicated in tumorigenesis. IGF binding proteins bind IGF in
serum and extracellular matrix reducing the mitogenic and antiapoptotic
properties of IGF. Our preliminary microarray studies of human ovarian
tumor tissue revealed a significant loss in gene expression of the IGF
binding proteins in tumors with high malignant potential. To confirm
these findings, we have designed further translational studies on
ovarian tumor tissue and patient serum using immunohistochemistry and
western blotting. We are currently using cell culture models to
investigate the molecular mechanisms of gonadotropins in ovarian cancer
progression and their possible relationship to the IGF system.
Read my CV (Adobe PDF format)
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Travis Palmer — Research Technician
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Students
Graduate students
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Geneva
DeMars
After
graduating in 1997 with a B.S. in Systems Engineering from the
University of Virginia, Geneva moved to Georgia and worked in the ICU
of UGA’s Small Animal Teaching Hospital in the School of
Veterinary Medicine and completed courses in the biological sciences.
She joined Dr. Puett’s lab as a Biochemistry and Molecular
Biology doctoral student in May of 2002 and researches the molecular
mechanisms by which G protein-coupled receptors, in particular the
glycoprotein hormone receptors, interface with their cognate G-proteins
on the intracellular face of the plasma membrane during receptor
activation. She is also conducting research using bioinformatics and
computational biology to study evolutionary aspects of the ectodomains
of G proteincoupled receptors containing a Leu-rich region flanked by
two Cys-rich regions and to make structure predictions of the
ectodomains. Some of her results were presented at an international
meeting in 2003, and she will present her additional findings in 2004.
She is currently the New Student Liaison for the Biochemistry &
Molecular Biology Graduate Student Association.
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Yongsheng
Li
I graduated from
Jilin University in
China with B.S. and M.S. degreee in biochemistry. I joined Dr. Puett’s
group in 2002 as a
doctoral student in Biochemistry & Molecular Biology. My
research encompasses the structural aspects of the ectodomain of the
luteinizing hormone receptor and its interaction with hCG hormone. I am
applying mass spectrometry and x-ray crystallography on
the single-chain hormone-receptor fusion protein, as well as
molecular modeling methods to study the structrual basis of hCG-LHR
interaction.
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Hope
E. Blackstone
I'm
currently a first year PhD student doing rotations and
teaching, my project is going to be a collaboration between the labs of
Dr. Steven Dalton and Dr. David Puett involving embryonic stem cell differentiation, specifically to the trophoblast
layer. I graduated from the University of Maine in 2005 with
a triple
major in Biochemistry, Cellular and Molecular Biology, and Microbiology.
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Rotating students
Undergraduates
Recent Alumni
Prema Narayan, Ph.D.
Assistant Prof. of Physiology
Southern Illinois School of Medicine
Carbondale, IL |
Maggie Shirley, M.S.
Medical student
Columbia University Coll. of Phys. and Surg. |
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Carlos
Alvarez, Ph.D.
Professor of Biology
Pensacola Christian College
Pansacola, FL
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Neil
Bhowmick, Ph.D.
Assistant Prof. of Urology
Vanderbilt University School of Medicine
Nashville, TN
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Gregory
Fraliss, Ph.D.
Postdoctoral Fello with Dr. Marc Caron
Duke University
Durham, NC
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Lisa
Kelly, Ph.D.
Veterinary student
College of Veterinary Medicine, University of Georgia
Athens, GA
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Tomas
Meehan, Ph.D.
Postdoctoral Fellow
Baylor College of Medicine
Houston, TX
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Rebecca
Schubert, Ph.D.
High school science teacher
______
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Chengbin
Wu, Ph.D.
Scientist with _____
_____, MA
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