BCMB 7300. Master's Thesis. 1-10 hours. Repeatable for maximum 20 hours credit.
Oasis Title: MASTER'S THESIS.
Prerequisite: Permission of department.
Thesis writing under the direction of the major professor.
Nontraditional format: Independent research and thesis preparation.
Offered fall, spring, and summer semesters every year.

BCMB 8005. Graduate Professional Development. 1 hour.
Oasis Title: GRAD DEVELOP.
Prerequisite: Permission of department.
A discussion of topics that are fundamental to modern graduate research, including safe laboratory practices, scientific ethics, the scientific method, and scientific resource awareness. Student assignments will explore approaches for identifying and securing independent research funding.
Offered fall semester every year.

BCMB 8010. Advanced Biochemistry and Molecular Biology I. 4 hours.
Oasis Title: ADV BIOC/MOL BIOL I.
Prerequisite: BCMB(BIOL)(CHEM) 3100 or BCMB 4010/6010.
Advanced biochemistry and molecular biology stressing thermodynamic principles in biochemistry, structural biology, enzymology, and aspects of metabolism and bioenergetics.
Offered fall semester every year.

BCMB 8020. Advanced Biochemistry and Molecular Biology II. 4 hours.
Oasis Title: ADV BIOCHEM II.
Prerequisite: BCMB 8010.
Advanced biochemistry and molecular biology stressing metabolism and bioenergetics, replication, transcription, RNA processing, genetic codes, translation, membrane transport, and signal transduction.
Offered spring semester every year.

BCMB 8030. Introduction to Research in Biochemistry and Molecular Biology. 3 hours.
Oasis Title: INTRO RES BMB.
Prerequisite: Permission of department.
Overview of current departmental research and introduction to research facilities. Training and practical experience in oral presentation, scientific writing, and grant preparation.
Offered spring semester every year.

BCMB 8035. Laboratory Rotation. 1-3 hours.
Repeatable for maximum 9 hours credit. 3-9 hours lab per week.
Oasis Title: LAB ROTATION.
Prerequisite: Permission of department.
Exploratory laboratory research for first year biochemistry graduate students.
Offered fall, spring, and summer semesters every year.

BCMB(CHEM) 8040. Advanced Physical Biochemistry. 3 hours.
Oasis Title: ADV PHYS BIOC.
Prerequisite: Permission of department.
Principles in physical chemistry and biophysics to biological macromolecules, including structural biology, hydrodynamics, electronic and magnetic resonance spectroscopy, and crystallography.
Offered spring semester every year.

BCMB 8050. Cellular and Molecular Biochemistry. 1 hour. Repeatable for maximum 5 hours credit.
Oasis Title: CELL & MOL BIOC.
Prerequisite: BCMB 8020 or permission of department.
Advanced molecular and cellular biochemistry, including structure, biosynthesis, and assembly of cell proteins and nucleic acids.
Non-traditional format: Selected readings and meetings with speakers in the annual BMB Symposium.
Offered spring semester every year.

BCMB 8060. Biochemistry and Molecular Biology Seminar. 1-2 hours. Repeatable for maximum 20 hours credit.
One credit=Attendance only. Two credits= Research seminar is required.
FIRST AND SECOND YEAR STUDENTS SHOULD ENROLL FOR 1 CREDIT HOUR (S/U) EACH SEMESTER AND ARE REQUIRED TO ATTEND A MINIMUM OF 75% OF THE SCHEDULED REGULAR SEMINARS TO OBTAIN A SATISFACTORY GRADE. THIRD AND FOURTH YEAR STUDENTS SHOULD ENROLL FOR 2 CREDIT HOURS (LETTER GRADE), ONCE EACH ACADEMIC YEAR, AND ARE REQUIRED TO PRESENT A RESEARCH SEMINAR DURING THE YEAR.
Oasis Title: BIOC & MOL BIOL SEM.
Prerequisite: none.
Seminar dealing with various topics in current biochemistry and molecular biology. Non-traditional format: Grading of A-F will be used when the student presents a seminar; grading of S/U will be used when attendance is required but a seminar is not given.
Offered fall and spring semesters every year.

BCMB 8070. Research Discussion. 1 hour. Repeatable for maximum 10 hours credit.
Oasis Title: RESEARCH DISCUSSION.
Prerequisite: BCMB 8010 or permission of department.
Seminar focused on current research in biochemistry and molecular biology.
Offered fall, spring, and summer semesters every year.

BCMB 8080. Current Literature in Biochemistry and Molecular Biology. 1 hour. Repeatable for maximum 6 hours credit.
Oasis Title: BIOC & MOL BIOL LIT.
Prerequisite: BCMB 8020.
Journal club in selected topics in cell and molecular biochemistry.
Not offered on a regular basis.

BCMB 8100. Advanced Topics in Biochemistry and Molecular Biology. 1 hour. Repeatable for maximum 10 hours credit.
Oasis Title: ADVANCED TOPICS.
Prerequisite: BCMB 8020.
Selected areas in current molecular and cell biochemistry. Topics will change on a regular basis.
Not offered on a regular basis.

BCMB 8105. Advanced Topics in Biotechnology. 2 hours.
Oasis Title: ADV BIOTECH.
Prerequisite: BCMB 8020 and permission of department.
An in-depth study of selected topics in Biotechnology with emphasis on student presentations and discussion.
Offered spring semester every odd-numbered year.

BCMB(CHEM) 8110. Advanced Topics in Protein Structure-Function Relationships. 3 hours.
Oasis Title: PROTEIN STR/FUNC.
Prerequisite: BCMB 8010.
The relationship of protein structure to biological function, including protein folding, conformation, stability, and enzyme mechanisms.
Offered fall semester every even-numbered year.

BCMB 8120. Advanced Topics in Gene Expression. 2 hours.
Oasis Title: NUCLEIC ACIDS.
Prerequisite: BCMB 8010.
Biochemistry and molecular biology of nucleic acids, with emphasis on biosynthesis, structure, and function.
Offered spring semester every even-numbered year.

BCMB 8130. Advanced Topics in Glycobiology. 2 hours.
Oasis Title: GLYCOBIOLOGY.
Prerequisite: BCMB 8010.
Complex carbohydrates and glycoconjugates, including biosynthesis, structure, and biological function.
Offered fall semester every odd-numbered year.

BCMB 8140. Advanced Topics in Genomics and Bioinformatics. 2 hours.
Oasis Title: GENOMICS&BIOINFORMA.
Prerequisite: BCMB 8010.
Contemporary approaches in the genomics of bacteria, archaea and eucarya, including computer applications on the use of various data bases.
Offered fall semester every odd-numbered year.

BCMB 8150. Advanced Topics in Cellular Communication and Regulation. 2 hours.
Oasis Title: CELL COMM & REG.
Prerequisite: BCMB 8010.
Molecular mechanisms of intra- and inter-cellular communication, including the role of hormones, cytokines, neurotransmitters and receptors.
Offered spring semester every even-numbered year.

BCMB 8160. Advanced Topics in the Biochemical Basis of Human Disease. 2 hours.
Oasis Title: BIOC HUMAN DIS.
Prerequisite: BCMB 8010.
The molecular and cellular basis of human disease with emphasis on genetic and acquired disorders.
Offered spring semester every odd-numbered year.

BCMB 8170. Advanced Topics in Plant Biochemistry and Molecular Biology. 2 hours.
Oasis Title: PLANT BIOCHEMISTRY.
Prerequisite: BCMB 8010.
Advanced treatment of plant biochemistry and molecular biology, including photosynthesis and nitrogen fixation.
Offered spring semester every odd-numbered year.

BCMB(CHEM) 8180. X-Ray Crystallography. 3 hours. 2 hours lecture and 2 hours lab per week.
Oasis Title: CRYSTALLOGRAPHY.
Prerequisite: BCMB 8010 and BCMB 8040.
The basic principles of x-ray crystallography with major application to protein structure determination, including laboratories on crystallization techniques and data collection.
Offered spring semester every year.

BCMB (CHEM) 8189. Fundamental Principles of NMR Spectroscopy. 3 hours. 2 hours lecture and 3 hours lab per week.
Oasis Title: NMR SPECTROSCOPY.
Prerequisite: BCMB 8010 or permission of department.
Practical and theoretical aspects of NMR spectroscopy used in the analysis of small organic molecules as well as biological macromolecules. Energy and vector diagrams are employed to understand basic 1D and 2D NMR experiments. Students will gain experience by operating NMR spectrometers and by completing a semester project on a topic of their choice.
Offered Fall semester every year.

BCMB(CHEM) 8190. NMR Spectroscopy of Biomolecules. 3 hours.
Oasis Title: BIOL NMR SPEC.
Prerequisite: BCMB(CHEM) 8040.
NMR spectroscopy with applications to proteins and other biopolymers. Special attention will be given to methods of structure determination.
Offered fall semester every odd-numbered year.

(BCMB)CHEM 8220. Physical Methods in Inorganic and Bioinorganic Chemistry. 4 hours. 3 hours lecture and 3 hours lab per week.
Oasis Title: PHYS METH INORG CHM.
Prerequisite: CHEM 8210.
Physical methods used in inorganic and bioinorganic chemical research including UV/visible/near IR absorption spectroscopy, (magnetic) circular dichroism, electron paramagnetic resonance, nuclear magnetic resonance, Mossbauer and X-ray absorption spectroscopies, single crystal x-ray diffraction, and magnetochemistry.
Offered spring semester every year.

(BCMB)CHEM 8250. Bioinorganic Chemistry. 3 hours.
Oasis Title: BIOINORG CHEM.
Prerequisite or corequisite: BCMB 6000 or BCMB 8010 or CHEM 6400 or permission of department.
Biological processes and molecules, mainly proteins and nucleic acids, which incorporate metal ions. Topics include metal binding to biopolymers, the roles of metal ions in biological processes such as electron transfer, atom or group transfer, and the use of metal complexes as therapeutic agents.
Offered fall semester every odd-numbered year.

(BCMB)CHEM 8330. Macromolecular Simulations. 3 hours.
Introduces techniques of molecular simulation relevant to biomolecular systems, and provides extensive hands-on experience with current modeling and simulational programs. Typical projects include protein homology modeling, 3-D structure refinement by molecular dynamics simulations and the calculation of interaction energies.
Offered spring semester.
Instructor: Woods, R.

(BCMB)CBIO(MIBO) 8520. Topics in Biochemistry and Molecular Genetics of Parasites. 3 hours. Repeatable for maximum 6 hours credit. 1 hour lecture and 2 hours lab per week.
Oasis Title: MOLEC PARASITOL.
Prerequisite: BCMB 8020 and GENE 8930.
Parasite cellular biochemistry and molecular genetics with potential for rational drug design. Topics include DNA replication, RNA editing, nucleic acid salvage pathways, polyamine metabolism, and glycosylphosphatidylinositol (GPI) anchors.
Offered spring semester every odd-numbered year.

(BCMB)CHEM 8810. Mass Spectrometry. 3 hours.
Oasis Title: MASS SPECTROMETRY.
Modern methods of mass spectrometry covering fundamental principles, instrumentation, and data interpretation. New techniques for the structural analysis of biomolecules.
Offered fall semester every year.

(BCMB)BTNY(GENE)(PATH) 8960. Genetics of Yeast and Filamentous Fungi. 3 hours.
Oasis Title: GENETICS OF FUNGI.
Prerequisite: Permission of department.
Classical genetics and molecular biology of budding yeast, fission yeast, and model filamentous fungi. Includes life cycle, cell cycle, cytoskeleton, mating types, morphogenesis, pathogenesis, mutant screens, and cloning strategies.
Offered spring semester every even-numbered year.

BCMB 8990. Problems in Biochemistry and Molecular Biology. 1-5 hours. Repeatable for maximum 20 hours credit.
Oasis Title: PROB BIOC&MOL BIOL.
Prerequisite: Permission of department.
Focused research, advanced readings, and tutorials with faculty members.
Non-traditional format: Students will meet with faculty members on a regular basis.
Offered fall, spring, and summer semesters every year.

BCMB 9000. Doctoral Research. 1-15 hours. Repeatable for maximum 45 hours credit.
Oasis Title: DOCTORAL RESEARCH.
Prerequisite: Permission of department.
Research while enrolled for a doctoral degree under the direction of faculty members.
Non-traditional format: Independent research under the direction of a faculty member.
Offered fall, spring, and summer semesters every year.

BCMB 9300. Doctoral Dissertation. 1-15 hours. Repeatable for maximum 30 hours credit.
Oasis Title: DOCT DISSERTATION.
Prerequisite: Permission of department.
Dissertation writing under the direction of the major professor.
Non-traditional format: Independent research and preparation of the doctoral dissertation.
Offered fall, spring, and summer semesters every year.