CHEM/BCMB 4190/6190/8189
Introductory NMR / Fundamentals of NMR
(Fall 2009)
Nuclear Magnetic Resonance (NMR) is a form of spectroscopy that uses the magnetic properties of nuclei to probe molecular structure. It has found applications in analysis of organic and inorganic compounds, in structure determination of biological macromolecules, and even in medical imaging. This introductory course is intended to serve a broad audience seeking a background in principles behind NMR methodology as well as a practical introduction to how data are acquired and analyzed. Material is presented partly in lecture and partly in laboratory formats. It is an ideal stepping-stone to more advanced courses offered in biomolecular NMR (CHEM/BCMB 8190) as well as other application-oriented courses.
The three courses share lecture and laboratory presentations. Grading is based on exams, written laboratory reports, and an evaluation of classroom and laboratory participation. For 8189, completion of an additional independent study project is required.
Website designed by Beverly Chalk Executive Web Designs
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Internet Links
Problem Sets
Notices
Lab Info
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Instructor:
Dr. Jeffrey Urbauer

Class Time:
TU, TH, 3:30-4:45
Inquiries to Professor Urbauer - urbauer@chem.uga.edu
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Recommended text:
ORDER TEXT
"Basic One- and Two-Dimensional NMR Spectroscopy"
-VCH paperback
(2nd, 3rd, or 4th edition)
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| Date |
Topic |
Text
Readings |
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Aug. |
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TU
18 |
Introduction and Basic Principles I  |
1.1, 1.2
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| TH
20 |
Basic
Principles I |
1.2,
1.3
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| TU
25 |
Basic
Principles II  |
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| TH
27 |
1H and 13C Chemical Shifts  |
2.1
- 2.4
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Sept. |
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| TU 1 |
NMR Lab #1  |
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| TH
3 |
NMR Lab #1 |
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| TU 8 |
1H/1H, 1H/13C, 13C/13C Couplings  |
3.1
- 3.5
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| TH 10 |
EXAM 1 |
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| TU 15 |
Double
Resonance Experiments  |
5.1
- 5.3
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| TH 17 |
Spin
Relaxation  |
7.1
- 7.3
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| TU 22 |
Intro to Complex Pulse Sequences  |
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| TH 24 |
Spin-Echo
Experiment  |
8.3,
8.4
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| TU 29 |
1D
Double Resonance NMR Lab #2  |
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| Oct. |
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| TH 1 |
1D
Double Resonance NMR Lab #2 |
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| TU 6 |
EXAM 2 |
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| TH 8 |
INEPT
Experiment  |
8.5
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| TU 13 |
DEPT
Experiment  |
8.6
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| TH 15 |
Introduction to 2D NMR / COSY  |
9.1, 9.2
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| TU
20 |
1D
13C and DEPT NMR Lab #3  |
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| TH 22 |
1D
13C and DEPT NMR Lab #3 |
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| TH 22 |
Midpoint Withdrawl Deadline |
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| TU 28 |
2D
COSY / HETCOR  |
9.4
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| TH 29 |
EXAM 3 |
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Nov.
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| TU 3 |
2D
TOCSY / HSQC  |
9.4
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| TH 5 |
The Nuclear Overhauser Effect  |
10.1, 10.2
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| TU 10 |
2D
HSQC / COSY Lab #4  |
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| TH 12 |
2D
HSQC / COSY Lab #4 |
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| TU 17 |
2D
NOESY  |
10.2 - 10.4
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| TH 19 |
Special Topic |
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| MON 23 - FRI 27 |
THANKSGIVING
HOLIDAY - NO CLASS |
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| Dec. |
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TU 1 |
NOESY / TOCSY Lab #5  |
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| TH 3 |
NOESY / TOCSY Lab #5 |
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| TU 8 |
University operates a Friday class schedule / No class |
Last day of classes |
| WED 9 |
Reading day |
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| TU 15 |
EXAM 4 (3:30 - 6:30) |
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