CHEM/BCMB 4190/6190/8189

Introductory NMR / Fundamentals of NMR

(Fall 2007)


Nuclear Magnetic Resonance (NMR) is a form of spectroscopy that uses the magnetic properties of nuclei to probe molecular structure. It has found applications in analysis of organic and inorganic compounds, in structure determination of biological macromolecules, and even in medical imaging. This introductory course is intended to serve a broad audience seeking a background in principles behind NMR methodology as well as a practical introduction to how data are acquired and analyzed. Material is presented partly in lecture and partly in laboratory formats. It is an ideal stepping-stone to more advanced courses offered in biomolecular NMR (CHEM/BCMB 8190) as well as other application-oriented courses.

The three courses share lecture and laboratory presentations. Grading is based on exams, written laboratory reports, and an evaluation of classroom and laboratory participation. For 8189, completion of an additional independent study project is required.

 

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Internet Links

Problem Sets

Notices

Lab Info

Instructor:
Dr. Jeffrey Urbauer



Class Time:
TU, TH, 3:30-4:45

Inquiries to Professor Urbauer -
urbauer@chem.uga.edu


Recommended text:

ORDER TEXT


"Basic One- and Two-Dimensional NMR Spectroscopy"
-VCH paperback

(2nd, 3rd, or 4th edition)

 
Course Syllabus 
 
web notes
     lecture and lab notes (see below)
Laboratory Sessions
EXAMS
HOLIDAYS (no class)
Special
 
Date
  Topic
Text Readings
     

Aug.

TH 16

 

Introduction and Basic Principles I

 

1.1, 1.2

TU 21 Basic Principles I

1.2, 1.3

TH 23 Basic Principles II

1.4 - 1.6

TU 28 NMR Lab #1

 

TH 30 NMR Lab #1

 

     
Sept.
   
     
TU 4 1H and 13C Chemical Shifts notes  another link

2.1 - 2.4

TH 6 1H/1H, 1H/13C, 13C/13C Couplings notes

3.1 - 3.5

TU 11
EXAM 1

 

TH 13 Double Resonance Experiments notes

5.1 - 5.3

TU 18
Spin Relaxation notes

7.1 - 7.3

TH 20 Intro to Complex Pulse Sequences

8.1, 8.2

TU 25 1D Double Resonance NMR Lab #2
TH 27 1D Double Resonance NMR Lab #2

Oct.

 

 

 

 

TU 2
EXAM 2
 
TH 4 Spin-Echo Experiment

8.3, 8.4

TU 9 INEPT Experiment  

8.5

TH 11 DEPT Experiment

8.6

FRI 12
Midpoint Withdrawl Deadline
 
TU 16 1D 13C and DEPT NMR Lab #3
TH 18 1D 13C and DEPT NMR Lab #3
TU 23
Special Topic
TH 25
FALL BREAK - NO CLASS
TU 30 Introduction to 2D NMR / COSY notes

9.1, 9.2

     

Nov.

   
     
TH 1
EXAM 3
TU 6 2D COSY / HETCOR

9.4

TH 8 2D TOCSY / HSQC

9.4

TU 13 2D HSQC / COSY Lab #4 NOTES     
TH 15 2D HSQC / COSY Lab #4
TU 20 The Nuclear Overhauser Effect NOTES

10.1, 10.2

TH 22
THANKSGIVING HOLIDAY - NO CLASS
TU 27
2D NOESY notes

10.2 - 10.4

TH 29
NOESY / TOCSY Lab #5 bites

Dec.

 

 

TU 4
University operates a Friday class schedule
 
TH 6 NOESY / TOCSY Lab #5
FRI 7
Reading day
 
   
TH 13
EXAM 4 (3:30 -6:30)
     


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